Standard Attributes
The demographic characteristics and nutrient levels of the study population are summarized in Table 1. The mean (± SD) age and preconceptional BMI of the pregnant women were (± 3.97) years and (± 2.81) kg/m 2 , respectively. Among the pregnant women, %, %, and %, respectively, had a family history of diabetes, smoking exposure, and alcohol consumption during gestation. FAS was found in % (674 out of 1,058) of the pregnant women, of whom % (650 out of 674) took compound vitamin supplements. The median (interquartile range) concentrations of RBC folate, serum folate, and vitamin B12 were (–), (–), and (–) (Supplementary Fig. 1).
Continuing variables is demonstrated since the means ± SD or median (interquartile assortment), and you may categorical variables is indexed since the letter (%). No missing analysis stayed in the modern studies.
Among 1,058 pregnancies, GDM occurred in 180 women (%) with a mean follow-up time of 11.1 ± 1.5 gestational weekspared with the group without GDM, median RBC folate and vitamin B12 levels in early pregnancy were significantly higher in the group with GDM (for RBC folate: vs. ng/mL, P = 0.045; for vitamin B12: vs. pg/mL, P = 0.002). No significant differences in serum folate concentration between GDM and non-GDM were found (Supplementary Fig. 2).
Relationships out-of Maternal Folate Position and Vitamin B12 That have GDM Risk
FAS was associated with an increased risk of GDM (adjusted OR [aOR] 1.73 [95% CI 1.19–2.53]; P = 0.004). No significant association was found between RBC folate and serum folate levels as continuous variables with GDM (for RBC folate: aOR 1.07 [95% CI 0.99–1.15]; P = 0.08; for serum folate: aOR 1.01 [95% CI 0.97–1.05]; P = 0.43) (Table 2)pared with pregnant women who had RBC folate levels <400 ng/mL, those with RBC folate ?600 ng/mL were associated with ?1.60-fold higher odds of GDM (aOR 1.58 [95% CI 1.03–2.41]; P = 0.033). [Read more…] about Research off RBC Folate, Solution Folate, and you may Vitamin Ba dozen